David Stern

Professor, President
David Stern
ds28@cornell.edu
Office/Lab: 301/213
Phone: 607-254-1300
Email: ds28@cornell.edu
Office/Lab: 301/213
Office Phone: 607-254-1300
Lab Phone: 607-254-1304
Affiliations: Section of Plant Biology / School of Integrative Plant Science / Cornell University
Graduate Fields: Plant Biology; Genetics & Development; Biochemistry, Cell & Molecular Biology
Research Areas:  Stress Responses / Cell Biology
Research Overview

The underlying research themes in the Stern laboratory are chloroplast biology, bioenergy and nuclear-cytoplasmic interactions. Within this framework, we study how chloroplast genes and metabolic activities are regulated by the products of nuclear genes, usually acting at the transcriptional or post-transcriptional level. Areas of emphasis include the roles of ribonucleases and RNA-binding proteins and assembly of the carbon-fixing enzyme Rubisco. We are also using molecular and genetic techniques to adjust chloroplast metabolism for the production of useful hydrocarbons.

Lab Members

In the News

  • BTI’s Big Red Anniversary: 40 Years at Cornell

    April 22nd, 2019
    The Boyce Thompson Institute of Corvallis, Oregon? It almost happened. April 24 will mark the 40th anniversary of the dedication ceremony for BTI’s current facilities on the Cornell University campus in Ithaca, NY. The Institute’s researchers and staff will celebrate the milestone with cake and in remarks at events throughout the coming months, with gratitude […] Read more »

  • Boyce Thompson Institute leadership provides scholarships to students pursuing degrees in STEM  

    August 3rd, 2018
    The Boyce Thompson Institute (BTI) is honored to announce the awarding of four, $1,000 scholarships to first-generation college students from Groton, Ithaca, Lansing and Newfield. One student from each school was chosen based on their intention to study a STEM-related field at a two or four-year school. Priority has been given to first-generation college students, […] Read more »

  • Bioreactors on a chip renew promises for algal biofuels

    October 1st, 2017
    This week, researchers from Boyce Thompson Institute and Texas A&M University report in Plant Direct exciting new technology that may revolutionize the search for the perfect algal strain: Algal droplet bioreactors on a chip. Read more »

Intern Projects

The underlying research themes in the Stern laboratory are chloroplast biology, bioenergy and nuclear-cytoplasmic interactions. Within this framework, we study how chloroplast genes and metabolic activities are regulated by the products of nuclear genes, usually acting at the transcriptional or post-transcriptional level. Areas of emphasis include the roles of ribonucleases and RNA-binding proteins and assembly of the carbon-fixing enzyme Rubisco. We are also using molecular and genetic techniques to adjust chloroplast metabolism for the production of useful hydrocarbons.

Internship Program | Projects & Faculty | Apply for an Internship

Interns

Publications

Overexpression of Rubisco subunits with RAF1 increases Rubisco content in maize
2018.
Salesse-Smith, C.E., Sharwood, R.E., Busch, F.A., Kromdijk, J., Bardal, V. and Stern, David
Nature Plants.
4
:
802–810
View
Reinventing postgraduate training in the plant sciences: T‐training defined through modularity, customization, and distributed mentorship
2018.
Henkhaus, N.A., Taylor, C.B., Greenlee, V.R., Sickler, D.B., Stern, David
Plant Direct.
2
:
e00095
View
A Guide to the Chloroplast Transcriptome Analysis Using RNA-Seq
2018.
Michel, E. JS, Hotto, A. M., Strickler, S. R., Stern, David, Castandet, B.
The Nucleus (Methods in Molecular Biology).
1829
:
295–313
View
The Rubisco Chaperone BSD2 May Regulate Chloroplast Coverage in Maize Bundle Sheath Cells
2017.
Salesse-Smith, C., Sharwood, R. E., Sakamoto, W., Stern, David
Plant Physiology.
175
:
pp.01346.2017–pp.01346.2017
View
Selecting high-growth/high-lipid producing microalgae from a mutant library through droplet microfluidics
2016.
Kim, H. S., Han, S., Guzman, A. R., Sobahi, N., Thapa, H. R., Browne, D., Tatli, M., Hsu, S., Stern,…
:
200–201
ChloroSeq, an Optimized Chloroplast RNA-Seq Bioinformatic Pipeline, Reveals Remodeling of the Organellar Transcriptome Under Heat Stress
2016.
Castandet, B., Hotto, A. M., Strickler, S. R., Stern, David
G3: Genes|Genomes|Genetics.
6
:
2817–2827
View
Activation of an Endoribonuclease by Non-intein Protein Splicing
2016.
Campbell, S. J., Stern, David
Journal of Biological Chemistry.
291
:
15911–15922
View
Arabidopsis Chloroplast Mini-Ribonuclease III Participates in rRNA Maturation and Intron Recycling
2015.
Hotto, A. M., Castandet, B., Gilet, L., Higdon, A., Condon, C., Stern, David
The Plant Cell.
27
:
724–740
View
A protein with an inactive pterin-4a-carbinolamine dehydratase domain is required for Rubisco biogenesis in plants
2014.
Feiz, L., Williams-Carrier, R., Belcher, S., Montano, M., Barkan, A., Stern, David
The Plant Journal.
80
:
862–869
View
The Plant Science Decadal Vision: Response to the Martin Commentary
2013.
Stern, David, Mackenzie, S.
The Plant Cell.
25
:
4775–4776
View
Arabidopsis chloroplast quantitative editotype
2013.
Ruwe, H., Castandet, B., Schmitz-Linneweber, C., Stern, David
Febs Letters.
587
:
1429–1433
View
RNase J participates in a pentatricopeptide repeat protein-mediated 5′ end maturation of chloroplast mRNAs
2013.
Luro, S., Germain, A., Sharwood, R. E., Stern, David
Nucleic Acids Research.
41
:
9141–9151
View
Setaria viridis Transformation Provides a Useful Tool for Maize Functional Genomics
2013.
Van Eck, Joyce, Swartwood, K., Azodi, C., Vollbrecht, E., Unger-Wallace, E., Strable, J., Stern, Dav…
IN VITRO CELLULAR & DEVELOPMENTAL BIOLOGY-ANIMAL.
49
:
S63–S64
RNA processing and decay in plastids
2013.
Germain, A., Hotto, A. M., Barkan, A., Stern, David
Wiley Interdisciplinary Reviews. RNA.
4
:
295–316
View
Strand-specific RNA sequencing uncovers chloroplast ribonuclease functions
2013.
Castandet, B., Hotto, A. M., Fei, Zhangjun, Stern, David
Febs Letters.
587
:
3096–3101
View
Ribonuclease II preserves chloroplast RNA homeostasis by increasing mRNA decay rates, and cooperates with polynucleotide phosphorylase in 3 ‘ end maturation
2012.
Germain, A., Kim, S. H., Gutierrez, R., Stern, David
The Plant Journal.
72
:
960–971
View
Ribulose-1,5-Bis-Phosphate Carboxylase/Oxygenase Accumulation Factor1 Is Required for Holoenzyme Assembly in Maize
2012.
Feiz, L., Williams-Carrier, R., Wostrikoff, K., Belcher, S., Barkan, A., Stern, David
The Plant Cell.
24
:
3435–3446
View
Ectopic Expression of Rubisco Subunits in Maize Mesophyll Cells Does Not Overcome Barriers to Cell Type-Specific Accumulation
2012.
Wostrikoff, K., Clark, A., Sato, S., Clemente, T., Stern, David
Plant Physiology.
160
:
419–432
View
Plastid non-coding RNAs: Emerging candidates for gene regulation
2012.
Hotto, A. M., Germain, A., Stern, David
Trends in Plant Science.
17
:
737–744
View
Overaccumulation of the chloroplast antisense RNA AS5 is correlated with decreased abundance of 5S rRNA in vivo and inefficient 5S rRNA maturation in vitro
2011.
Sharwood, R. E., Hotto, A. M., Bollenbach, T. J., Stern, David
RNA (New York, N.Y.).
17
:
230–243
View
View All Publications
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