David Stern

President
David Stern
ds28@cornell.edu
Office/Lab: 301/213
Phone: 607-254-1300
Email: ds28@cornell.edu
Office/Lab: 301/213
Office Phone: 607-254-1300
Lab Phone: 607-254-1304
Affiliations: Section of Plant Biology / School of Integrative Plant Science / Cornell University
Graduate Fields: Plant Biology; Genetics & Development; Biochemistry, Cell & Molecular Biology
Research Areas:  Stress Responses / Cell Biology
Research Overview

The underlying research themes in the Stern laboratory are chloroplast biology, bioenergy and nuclear-cytoplasmic interactions. Within this framework, we study how chloroplast genes and metabolic activities are regulated by the products of nuclear genes, usually acting at the transcriptional or post-transcriptional level. Areas of emphasis include the roles of ribonucleases and RNA-binding proteins and assembly of the carbon-fixing enzyme Rubisco. We are also using molecular and genetic techniques to adjust chloroplast metabolism for the production of useful hydrocarbons.

  • Cluster Hire Yields Three New Faculty Members

    Boyce Thompson Institute is pleased to announce the hiring of three faculty members as part of its new and innovative “cluster hire” approach. Out of 113 applicants, the three people who will join BTI over the next year are: Magdalena (Magda) Julkowska, a postdoctoral fellow at King Abdullah University of Science and Technology in Saudi […] Read more »
  • BTI’s Big Red Anniversary: 40 Years at Cornell

    The Boyce Thompson Institute of Corvallis, Oregon? It almost happened. April 24 will mark the 40th anniversary of the dedication ceremony for BTI’s current facilities on the Cornell University campus in Ithaca, NY. The Institute’s researchers and staff will celebrate the milestone with cake and in remarks at events throughout the coming months, with gratitude […] Read more »
  • Boyce Thompson Institute leadership provides scholarships to students pursuing degrees in STEM  

    The Boyce Thompson Institute (BTI) is honored to announce the awarding of four, $1,000 scholarships to first-generation college students from Groton, Ithaca, Lansing and Newfield. One student from each school was chosen based on their intention to study a STEM-related field at a two or four-year school. Priority has been given to first-generation college students, […] Read more »
  • Bioreactors on a chip renew promises for algal biofuels

    This week, researchers from Boyce Thompson Institute and Texas A&M University report in Plant Direct exciting new technology that may revolutionize the search for the perfect algal strain: Algal droplet bioreactors on a chip. Read more »
  • President David Stern: People Behind the Science Interview

    Tune in to BTI's David Stern on People Behind the Science: Growing Our Understanding of Photosynthesis to Improve ‪‎Plant‬ Metabolism Read more »

Intern Projects

The underlying research themes in the Stern laboratory are chloroplast biology, bioenergy and nuclear-cytoplasmic interactions. Within this framework, we study how chloroplast genes and metabolic activities are regulated by the products of nuclear genes, usually acting at the transcriptional or post-transcriptional level. Areas of emphasis include the roles of ribonucleases and RNA-binding proteins and assembly of the carbon-fixing enzyme Rubisco. We are also using molecular and genetic techniques to adjust chloroplast metabolism for the production of useful hydrocarbons.

Internship Program | Projects & FacultyApply for an Internship

Systematic sequencing of chloroplast transcript termini from Arabidopsis thaliana reveals >200 transcription initiation sites and the extensive imprints of RNA-binding proteins and secondary structures
2019.
Castandet, B., Germain, A., Hotto, A.M., Stern, David
Nucleic Acids Research.
:
Increased Rubisco content in maize mitigates chilling stress and speeds recovery
2019.
Salesse‐Smith, C., Sharwood, R., Busch, F., Stern, David
Plant Biotechnology Journal.
:
Directions for research and training in plant omics: Big Questions and Big Data
2019.
Argueso, C.T., Assmann, S.M., Birnbaum, K.D., Chen, S., Dinneny, J.R., Doherty, C.J., Eveland, A.L.,…
Plant Direct.
:
Overexpression of Rubisco subunits with RAF1 increases Rubisco content in maize
2018.
Salesse-Smith, C.E., Sharwood, R.E., Busch, F.A., Kromdijk, J., Bardal, V. and Stern, David
Nature Plants.
4
:
802–810
Reinventing postgraduate training in the plant sciences: T‐training defined through modularity, customization, and distributed mentorship
2018.
Henkhaus, N.A., Taylor, C.B., Greenlee, V.R., Sickler, D.B., Stern, David
Plant Direct.
2
:
e00095
A Guide to the Chloroplast Transcriptome Analysis Using RNA-Seq
2018.
Michel, E. JS, Hotto, A. M., Strickler, S. R., Stern, David, Castandet, B.
The Nucleus (Methods in Molecular Biology).
1829
:
295–313
The Rubisco Chaperone BSD2 May Regulate Chloroplast Coverage in Maize Bundle Sheath Cells
2017.
Salesse-Smith, C., Sharwood, R. E., Sakamoto, W., Stern, David
Plant Physiology.
175
:
pp.01346.2017–pp.01346.2017
Selecting high-growth/high-lipid producing microalgae from a mutant library through droplet microfluidics
2016.
Kim, H. S., Han, S., Guzman, A. R., Sobahi, N., Thapa, H. R., Browne, D., Tatli, M., Hsu, S., Stern,…
:
200–201
ChloroSeq, an Optimized Chloroplast RNA-Seq Bioinformatic Pipeline, Reveals Remodeling of the Organellar Transcriptome Under Heat Stress
2016.
Castandet, B., Hotto, A. M., Strickler, S. R., Stern, David
G3: Genes|Genomes|Genetics.
6
:
2817–2827
Activation of an Endoribonuclease by Non-intein Protein Splicing
2016.
Campbell, S. J., Stern, David
Journal of Biological Chemistry.
291
:
15911–15922
Arabidopsis Chloroplast Mini-Ribonuclease III Participates in rRNA Maturation and Intron Recycling
2015.
Hotto, A. M., Castandet, B., Gilet, L., Higdon, A., Condon, C., Stern, David
The Plant Cell.
27
:
724–740
A protein with an inactive pterin-4a-carbinolamine dehydratase domain is required for Rubisco biogenesis in plants
2014.
Feiz, L., Williams-Carrier, R., Belcher, S., Montano, M., Barkan, A., Stern, David
The Plant Journal.
80
:
862–869
The Plant Science Decadal Vision: Response to the Martin Commentary
2013.
Stern, David, Mackenzie, S.
The Plant Cell.
25
:
4775–4776
Arabidopsis chloroplast quantitative editotype
2013.
Ruwe, H., Castandet, B., Schmitz-Linneweber, C., Stern, David
Febs Letters.
587
:
1429–1433
RNase J participates in a pentatricopeptide repeat protein-mediated 5′ end maturation of chloroplast mRNAs
2013.
Luro, S., Germain, A., Sharwood, R. E., Stern, David
Nucleic Acids Research.
41
:
9141–9151
Setaria viridis Transformation Provides a Useful Tool for Maize Functional Genomics
2013.
Van Eck, Joyce, Swartwood, K., Azodi, C., Vollbrecht, E., Unger-Wallace, E., Strable, J., Stern, Dav…
IN VITRO CELLULAR & DEVELOPMENTAL BIOLOGY-ANIMAL.
49
:
S63–S64
RNA processing and decay in plastids
2013.
Germain, A., Hotto, A. M., Barkan, A., Stern, David
Wiley Interdisciplinary Reviews. RNA.
4
:
295–316
Strand-specific RNA sequencing uncovers chloroplast ribonuclease functions
2013.
Castandet, B., Hotto, A. M., Fei, Zhangjun, Stern, David
Febs Letters.
587
:
3096–3101
Ribonuclease II preserves chloroplast RNA homeostasis by increasing mRNA decay rates, and cooperates with polynucleotide phosphorylase in 3 ‘ end maturation
2012.
Germain, A., Kim, S. H., Gutierrez, R., Stern, David
The Plant Journal.
72
:
960–971
Ribulose-1,5-Bis-Phosphate Carboxylase/Oxygenase Accumulation Factor1 Is Required for Holoenzyme Assembly in Maize
2012.
Feiz, L., Williams-Carrier, R., Wostrikoff, K., Belcher, S., Barkan, A., Stern, David
The Plant Cell.
24
:
3435–3446
 

Contact:

Boyce Thompson Institute
533 Tower Rd.
Ithaca, NY 14853
607.254.1234
contact@btiscience.org