The HighFive cell line (sometimes referred to as High-Five or Hi5) is a well-established and popular tool for protein production. With the recent development of optimized virus-free sub-clones, it remains the safest and most effective platform for the Baculovirus Expression Vector System (BEVS).
BTI has partnered with researchers and companies to continue to improve the technology and make it accessible to all. The sole proprietor of the technology, BTI offers affordable licensing with complete peace of mind.
Our History: BTI – Home of the HighFive Cell Lines
Dr. Robert Granados was looking for ways to defend crops from the Cabbage Looper. During his research he made an unexpected discovery. The HighFive cell line and newer sub-clones free of nodavirus are a popular tool for recombinant protein production. Read more.
BTI is the exclusive owner of the proprietary HighFive cell line and related sub-clones. Contact us to inquire about cell lines available for testing and request commercial-use licenses.