Translational Program and Licensing

DISCOVERIES MAKING AN IMPACT

Plant research is in our DNA, and we take great pride in the broader impact our researchers are having on society.

TECHNOLOGIES AVAILABLE FOR LICENSING

Every technology selected for licensing offers a true value proposition to your company.

START-UP CREATION

Do you have an entrepreneurial mind and an exciting new technology? The New Business Development Task Force provides guidance and resources to help you succeed.

Discoveries Making an Impact

Coralie Salesse-Smith and David Stern are smiling in a greenhouse full of corn plants. Salesse-Smith is reaching out and touching a plant with both hands while Stern watches.

•  Vaccine and other protein production in insect cell lines
•  Natural small molecules in plant and human health
  Plant disease resistance
•  Plant and bacterial proteins in innate and effector-triggered immunity
•  Salicylic acid pathway for systemic acquired resistance
•  Plant insect resistance—plant genes and small signaling molecules
•  Plant-based vaccines

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BTI, home of the HighFive™ cell lines.

Dr. Robert Granados was looking for ways to defend crops from the Cabbage Looper. During his research he made an unexpected discovery. The HighFive cell line (sometimes referred to as High-Five or Hi5)  and newer sub-clones free of nodavirus are a popular tool for recombinant protein production.

BTI is the exclusive owner of the proprietary HighFive cell line and related sub-clones. Contact us to inquire about cell lines available for testing and request commercial-use licenses.

LEARN MORE

For licensing inquires contact licensing@btiscience.org

Technologies Available for Licensing

INSECT CELL LINES FOR PROTEIN PRODUCTION

  • BTI is the exclusive owner of the HighFive cell line
  • HighFive and related virus-free cell lines (Tnao38; Tnms42) are ideal for effective recombinant protein expression
  • The virus-free cell lineTnms42-sf was adapted to serum-free growth in large bioreactors
  • LEARN MORE

INCREASED RESISTANCE TO ABIOTIC STRESS IN CORN

  • The Raf1 technology improves photosynthesis, growth and recovery from abiotic stresses
  • LEARN MORE

INCREASED RESISTANCE TO BACTERIAL PATHOGENS IN PLANTS

  • The Ptr1 technology can be used to confer resistance to bacterial speck, wilt and spot disease in tomatoes, peppers, potatoes, tobacco plants, and possibly a broader range of important crops
  • The technology can be applied using a cisgenic approach, editing of the endogenous pseudogene or plant breeding
  • LEARN MORE

SMALL MOLECULES AGAINST PARASITIC WORMS

  • Licensing opportunity for human and animal use
  • Small molecule compounds that control mammal-pathogenic nematodes. US Patent: 9,487,551

Start-up Creation

How BTI supports the creation of start-ups interested in licensing BTI technologies:

Protecting Intellectual Property

Technology Review

Business Planning

funding Strategy

Connecting with Local & Regional Resources

Contact BTI’s Director of New Business Development for more information.

Current Ventures

Location: Pasadena, CA
CEO: Andrea Choe, PhD
Key Technology: Small compounds against auto-immune diseases and diabetes.
Website: https://holoclara.com

The Ascribe logo in green font

Location: McGovern Center, Cornell University, Ithaca NY
CEO: Jay Farmer, PhD
Key Technology: Small compounds promoting plant growth and enhancing plant immunity
Website: https://ascribebio.com/

Our Team

For licensing inquires contact licensing@btiscience.org

Julien Fey Headshot

Julien Fey

Director of the Translational Program

jpf23@cornell.edu

Headshot of Kelli Monce

Kelli Monce

Senior Administrator of the Translational Program

ksm84@cornell.edu

Headshot of Paul Debbie

Paul Debbie

Director of Research, Director of New Business Development

ppd2@cornell.edu

Headshot of Paul Debbie

Mamta Srivastava

Translational Program Associate

ms226@cornell.edu

Headshot of Paul Debbie

Philippe Nicolas

Translational Research Scientist

pn239@cornell.edu

Headshot of Paul Debbie

Yao Chen

Translational Researcher

yc778@cornell.edu

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