Translational Program and Licensing
DISCOVERIES MAKING AN IMPACT
Plant research is in our DNA, and we take great pride in the broader impact our researchers are having on society.
TECHNOLOGIES AVAILABLE FOR LICENSING
Every technology selected for licensing offers a true value proposition to your company.
START-UP CREATION
Do you have an entrepreneurial mind and an exciting new technology? The New Business Development Task Force provides guidance and resources to help you succeed.
Discoveries Making an Impact
• Vaccine and other protein production in insect cell lines
• Natural small molecules in plant and human health
• Plant disease resistance
• Plant and bacterial proteins in innate and effector-triggered immunity
• Salicylic acid pathway for systemic acquired resistance
• Plant insect resistance—plant genes and small signaling molecules
• Plant-based vaccines
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BTI, home of the HighFive™ cell lines.
Dr. Robert Granados was looking for ways to defend crops from the Cabbage Looper. During his research he made an unexpected discovery. The HighFive cell line (sometimes referred to as High-Five or Hi5) and newer sub-clones free of nodavirus are a popular tool for recombinant protein production.
BTI is the exclusive owner of the proprietary HighFive cell line and related sub-clones. Contact us to inquire about cell lines available for testing and request commercial-use licenses.
For licensing inquires contact licensing@btiscience.org
Technologies Available for Licensing
INSECT CELL LINES FOR PROTEIN PRODUCTION
- BTI is the exclusive owner of the HighFive cell line
- HighFive and related virus-free cell lines (Tnao38; Tnms42) are ideal for effective recombinant protein expression
- The virus-free cell lineTnms42-sf was adapted to serum-free growth in large bioreactors
- LEARN MORE
INCREASED RESISTANCE TO ABIOTIC STRESS IN CORN
- The Raf1 technology improves photosynthesis, growth and recovery from abiotic stresses
- LEARN MORE
INCREASED RESISTANCE TO BACTERIAL PATHOGENS IN PLANTS
- The Ptr1 technology can be used to confer resistance to bacterial speck, wilt and spot disease in tomatoes, peppers, potatoes, tobacco plants, and possibly a broader range of important crops
- The technology can be applied using a cisgenic approach, editing of the endogenous pseudogene or plant breeding
- LEARN MORE
SMALL MOLECULES AGAINST PARASITIC WORMS
- Licensing opportunity for human and animal use
- Small molecule compounds that control mammal-pathogenic nematodes. US Patent: 9,487,551
Start-up Creation
How BTI supports the creation of start-ups interested in licensing BTI technologies:
Protecting Intellectual Property
Technology Review
Business Planning
funding Strategy
Connecting with Local & Regional Resources
Contact BTI’s Director of New Business Development for more information.
Current Ventures
Location: Pasadena, CA
CEO: Andrea Choe, PhD
Key Technology: Small compounds against auto-immune diseases and diabetes.
Website: https://holoclara.com
Location: McGovern Center, Cornell University, Ithaca NY
CEO: Jay Farmer, PhD
Key Technology: Small compounds promoting plant growth and enhancing plant immunity
Website: https://ascribebio.com/
Our Team
For licensing inquires contact licensing@btiscience.org
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Contact:
Boyce Thompson Institute
533 Tower Rd.
Ithaca, NY 14853
607.254.1234
contact@btiscience.org
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