Translational Program and Licensing

Making an Impact

Licensing & Partnership Opportunities

Start-up Creation

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DISCOVERIES MAKING AN IMPACT

Plant research is in our DNA, and we take great pride in the broader impact our researchers are having on society.

LICENSING AND PARTNERSHIP OPPORTUNITIES

Every technology selected for licensing offers a true value proposition to your company.

START-UP CREATION

Do you have an entrepreneurial mind and an exciting new technology? The New Business Development Task Force provides guidance and resources to help you succeed.

Discoveries Making an Impact

Coralie Salesse-Smith and David Stern are smiling in a greenhouse full of corn plants. Salesse-Smith is reaching out and touching a plant with both hands while Stern watches.

Crop Improvement
• Yield
• Fruit quality
• Abiotic stress resistance
• Pathogen resistance
• Pangenomics
• Breeding tools

Small Molecules for:
• Crop protection
• Human and animal health

Recombinant Protein Production
• Recombinant vaccine and other protein production in insect cell lines
• Plant-based vaccines

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BTI, home of the HighFive™ cell lines.

Dr. Robert Granados was looking for ways to defend crops from the Cabbage Looper. During his research he made an unexpected discovery. The HighFive cell line (sometimes referred to as High-Five or Hi5) and newer sub-clones free of nodavirus are a popular tool for recombinant protein production.

BTI is the exclusive owner of the proprietary HighFive cell line and related sub-clones. Contact us to inquire about cell lines available for testing and request commercial-use licenses.

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For licensing inquires contact licensing@btiscience.org

Licensing and Partnership Opportunities

Crop Improvement

INCREASED RESISTANCE TO BACTERIAL PATHOGENS

Broad resistance to bacterial speck, wilt and spot diseases in tomato and eggplant
Resistance to bacterial canker in kiwi
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PREVENTING TRANSMISSION OF APHIDS AND POLEROVIRUS

Effectively block the transmission of aphids carrying poleroviruses.
We are seeking partners to help develop this technology in potato and cotton (transgenics)
CONTACT US FOR MORE INFORMATION

INCREASED RESISTANCE TO ABIOTIC STRESS IN CORN

Improves photosynthesis, growth and recovery from abiotic stresses
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PREVENTING BLOSSOM END ROT

This technology can be applied to tomatoes grown in greenhouses.
Research is underway to expand the use of the technology to other crops affected by blossom end rot, and for use in the field.
CONTACT US FOR MORE INFORMATION

IMPROVED YIELD AND DROUGHT RESISTANCE IN COTTON

CONTACT US FOR MORE INFORMATION

IMPROVED YIELD IN TOMATO

Experiments are underway to test the technology in commercial varieties and in other crops.
CONTACT US FOR MORE INFORMATION

SUPER PANGENOMICS FOR CROP IMPROVEMENT

BTI scientists have developed advanced know-how that promises to accelerate crop improvement using the genetic diversity of crop wild relatives.
Our technology can be used to discover new gene-trait relationships or to optimize the effect of already know genetic variants
We are actively seeking partners to develop a rapid crop improvement pipeline
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BREEDBASE – BREEDING MANAGEMENT AND ANALYSIS SOFTWARE

Design field layouts, collect phenotypic information using tablets, support the collection of genotyping samples in a field, store large amounts of high-density genotypic information, and provide Genomic Selection related analyses and predictions
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Human and Animal Health

SMALL MOLECULES AGAINST PARASITIC WORMS

Small molecule compounds that control mammal-pathogenic nematodes. US Patent: 9,487,551

Modular Glucosides for Therapeutic Compositions

Modular Glucosides Are a New Class of Small Bioactive Compounds with Strong Potential for Drug Development

Recombinant Protein Production

INSECT CELL LINES FOR PROTEIN PRODUCTION

BTI is the exclusive owner of the HighFive cell line
HighFive and related virus-free cell lines (Tnao38; Tnms42) are ideal for effective recombinant protein expression
The virus-free cell lineTnms42-sf was adapted to serum-free growth in large bioreactors
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Start-up Creation

How BTI supports the creation of start-ups interested in licensing BTI technologies:

Protecting Intellectual Property

Technology Review

Business Planning

funding Strategy

Connecting with Local & Regional Resources

Contact BTI’s Director of New Business Development for more information.
BTI’s Financial Conflict of Interest Policy

Current Ventures

Location: Pasadena, CA
CEO: Andrea Choe, PhD
Key Technology: Small compounds against auto-immune diseases and diabetes.
Website: https://holoclara.com

Location: McGovern Center, Cornell University, Ithaca NY
CEO: Jay Farmer, PhD
Key Technology: Small compounds promoting plant growth and enhancing plant immunity
Website: https://ascribebio.com/