Mass Spec Lab
Center for Advanced Mass Spectrometry
Analytical facility for metabolomics and chemical analysis.
Advanced Analysis
The Mass Spectrometry Facility at BTI provides state-of-the-art instrumentation and expert training for advanced chemical and biochemical analysis.
Our cutting-edge HPLC-MS/MS and GC-MS systems support high-resolution, high-sensitivity research in metabolomics, proteomics, and environmental science.
Training
Training and assistance with the use of the mass spectrometers, software, and data analysis are available to all researchers at BTI and Cornell University. Users with previous mass spectrometry and/or GC/HPLC experience are required to take at least four hours of training. Additional training blocks are available for less experienced users. Training includes method development specifically tailored for each biological application.
Reservations
Currently, the mass spectrometer is in high demand. To find out about future availability, please contact Frank Schroeder.
Contact Us
To schedule an appointment for training or for questions, please contact Frank Schroeder.
Our mailing address:
Frank Schroeder
Manager, Mass Spectrometer Facility
Office: Room 409/412
Boyce Thompson Institute
533 Tower Road
Ithaca, NY 14853-1801
HPLC-MS/MS
Two Thermo Scientific Q Exactive™ Hybrid Quadrupole-Orbitrap™ Mass Spectrometers coupled to Vanquish™ and Dionex™ UltiMate™ ultra-high-pressure chromatography systems are capable of ionization using heated electrospray (HESI), atmospheric pressure chemical ionization (APCI), and nano-flow electrospray (Nano-ESI). The Orbitrap Mass Analyzer combined with advanced quadrupole, S-lens, and a high-performance HCD collision cell for MS/MS plus features such as up to 18 hz scan rate, data-independent analysis (DIA), selected-ion monitoring (SIM), and spectral multiplexing up to ten precursors/scan make this system a state-of-the-art instrument for chemical and biochemical molecules analysis with up to 280,000 resolution, < 1 ppm mass accuracy, and femtogram sensitivity. These ultra-high-pressure liquid chromatography systems coupled with multiple switch valves and UV data acquisition makes it the system of choice for fully automated high-throughput approaches in the fields of metabolomics, proteomics, and food and environmental safety.
