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Schroeder Lab Publications
179. Oligonucleotide Catabolism-Derived Gluconucleosides in Caenorhabditis elegans. Brian J Curtis, Tyler J Schwertfeger, Russell N Burkhardt, Bennett W Fox, Jude Andrzejewski, Chester JJ Wrobel, Jingfang Yu, Pedro R Rodrigues, Arnaud Tauffenberger, Frank C Schroeder, J. Am. Chem. Soc. 2023, 145, 11611-11621. doi.org/10.1021/jacs.3c01151
178. Repurposing degradation pathways for modular metabolite biosynthesis in nematodes. Chester JJ Wrobel, Frank C Schroeder, Nat Chem Biol. 2023, 19, 678-686. doi.org/10.1038/s41589-023-01301-w
177. Sex-specificity of the C. elegans metabolome. Russell N Burkhardt, Alexander B Artyukhin, Erin Z Aprison, Brian J Curtis, Bennett W Fox, Andreas H Ludewig, Diana Fajardo Palomino, Jintao Luo, Amaresh Chaturbedi, Oishika Panda, Chester JJ Wrobel, Victor Baumann, Douglas S Portman, Siu Sylvia Lee, Ilya Ruvinsky, Frank C Schroeder, Nat Commun. 2023, 14, 320. doi.org/10.1038/s41467-023-36040-y
176. Parallel pathways for serotonin biosynthesis and metabolism in C. elegans. Jingfang Yu, Merly C Vogt, Bennett W Fox, Chester JJ Wrobel, Diana Fajardo Palomino, Brian J Curtis, Bingsen Zhang, Henry H Le, Arnaud Tauffenberger, Oliver Hobert, Frank C Schroeder, Nat Chem Biol. 2023, 19, 141-150. doi.org/10.1038/s41589-022-01148-7
175. Neuronally produced betaine acts via a ligand-gated ion channel to control behavioral states. Iris Hardege, Julia Morud, Jingfang Yu, Tatiana S Wilson, Frank C Schroeder, William R Schafer, PNAS. 2022, 119(48), e2201783119. doi.org/10.1073/pnas.2201783119
174. Inulin fibre promotes microbiota-derived bile acids and type 2 inflammation. Mohammad Arifuzzaman, Tae Hyung Won, Ting-Ting Li, Hiroshi Yano, Sreehaas Digumarthi, Andrea F Heras, Wen Zhang, Christopher N Parkhurst, Sanchita Kashyap, Wen-Bing Jin, Gregory Garbès Putzel, Amy M Tsou, Coco Chu, Qianru Wei, Alex Grier, Stefan Worgall, Chun-Jun Guo, Frank C Schroeder, David Artis, Nature. 2022, 611, 578-584. doi.org/10.1038/s41586-022-05380-y
173. Copper starvation induces antimicrobial isocyanide integrated into two distinct biosynthetic pathways in fungi. Tae Hyung Won, Jin Woo Bok, Nischala Nadig, Nandhitha Venkatesh, Grant Nickles, Claudio Greco, Fang Yun Lim, Jennifer B González, B Gillian Turgeon, Nancy P Keller, Frank C Schroeder, Nature Communications 2022, 13, 4828. doi.org/10.1038/s41467-022-32394-x
172. C. elegans as a model for inter-individual variation in metabolism. Bennett W Fox, Olga Ponomarova, Yong-Uk Lee, Gaotian Zhang, Gabrielle E Giese, Melissa Walker, Nicole M Roberto, Huimin Na, Pedro R Rodrigues, Brian J Curtis, Aiden R Kolodziej, Timothy A Crombie, Stefan Zdraljevic, L Safak Yilmaz, Erik C Andersen, Frank C Schroeder, Albertha JM Walhout, Nature 2022, 607, 571-577. doi.org/10.1038/s41586-022-04951-3
171. CEST-2.2 overexpression alters lipid metabolism and extends longevity of mitochondrial mutants. Antonia Piazzesi, Yiru Wang, Joshua Jackson, Lena Wischhof, Viktoria Zeisler-Diehl, Enzo Scifo, Ina Oganezova, Thorben Hoffmann, Pablo Gomez Martin, Fabio Bertan, Chester JJ Wrobel, Frank C Schroeder, Dan Ehninger, Kristian Handler, Joachim L Schultze, Lukas Schreiber, Gerhild van Echten-Deckert, Pierluigi Nicotera, Daniele Bano, EMBO reports 2022, e52606. doi.org/10.15252/embr.202152606
170. Nematode ascarosides attenuate mammalian type 2 inflammatory responses. Kenta Shinoda, Andrea Choe, Kiyoshi Hirahara, Masahiro Kiuchi, Kota Kokubo, Tomomi Ichikawa, Jason S Hoki, Akane S Suzuki, Neelanjan Bose, Judith A Appleton, Raffi V Aroian, Frank C Schroeder, Paul W Sternberg, Toshinori Nakayama, PNAS 2022, 119, e2108686119. doi.org/10.1073/pnas.2108686119
169. Comparative metabolomics with Metaboseek reveals functions of a conserved fat metabolism pathway in C. elegans. Maximilian J. Helf, Bennett W. Fox, Alexander B. Artyukhin, Ying K. Zhang, Frank C. Schroeder, Nature Communications 2022, 13, 782. doi.org/10.1038/s41467-022-28391-9
168. Formation and Function of Dauer Ascarosides in the Nematodes C. briggsae and C. elegans. Sarah M Cohen, Chester JJ Wrobel, Sharan J Prakash, Frank C Schroeder, Paul W Sternberg, G3 Genes| Genomes| Genetics 2022, jkac014. doi.org/10.1093/g3journal/jkac014
167. Experimental methods for dissecting the terraincognita of protein-metabolite interactomes. Mateusz Wagner, Bingsen Zhang, Arnaud Tauffenberger, Frank C Schroeder, Aleksandra Skirycz, Curr. Opin. Syst. Biol. 2021, 28, 100403. doi.org/10.1016/j.coisb.2021.100403
166. Combinatorial Assembly of Modular Glucosides via Carboxylesterases Regulates C. elegans Starvation Survival. Chester JJ Wrobel, Jingfang Yu, Pedro R Rodrigues, Andreas H Ludewig, Brian J Curtis, Sarah M Cohen, Bennett W Fox, Michael P O’Donnell, Paul W Sternberg, Frank C Schroeder, J. Am. Chem. Soc. 2021, 143, 46, 14676-14683. doi/abs/10.1021/jacs.1c05908
165. Nematode Signaling Molecules Are Extensively Metabolized by Animals, Plants, and Microorganisms. Yan Yu, Ying K Zhang, Murli Manohar, Alexander B Artyukhin, Anshu Kumari, Francisco J Tenjo-Castano, Hung Nguyen, Pratyush Routray, Andrea Choe, Daniel F Klessig, Frank C Schroeder, ACS Chem. Biol. 2021, 16, 1050-1058. doi.org/10.1021/acschembio.1c00217
164. Correcting for Naturally Occurring Mass Isotopologue Abundances in Stable-Isotope Tracing Experiments with PolyMID. Heesoo Jeong, Yan Yu, Henrik J Johansson, Frank C Schroeder, Janne Lehtio, Nathaniel M Vacanti, Metabolites 2021, 11(5), 301. doi.org/10.3390/metabo11050310
163. Syntheses of Amorfrutins and Derivatives via Tandem Diels-Alder and Anionic Cascade Approaches. Brian J Curtis, Robert J Micikas, Russell N Burkhardt, Rubin A Smith, Judy Y Pan, Katrina Jander, Frank C Schroeder, J. Org. Chem. 2021, 16, 11269–11276. doi: 10.1021/acs.joc.0c03043
162. Dual-purpose isocyanides produced by Aspergillus fumigatus contribute to cellular copper sufficiency and exhibit antimicrobial activity. Nicholas Raffa, Tae Hyung Won, Andrew Sukowaty, Kathleen Candor, Chengsen Cui, Saayak Halder, Mingji Dai, Julio A Landero-Figueroa, Frank C Schroeder, Nancy P Keller, PNAS. 2021, 118, e2015224118. doi: 10.1101/2020.07.23.217810
161. An Untargeted Approach for Revealing Electrophilic Metabolites. Yan Yu, Henry H Le, Brian J Curtis, Chester JJ Wrobel, Bingsen Zhang, Danielle N Maxwell, Judy Y Pan, Frank C Schroeder, ACS Chem. Biol. 2020, 15, 3030-3037. doi: 10.1021/acschembio.0c00706
160. Modular metabolite assembly in C. elegans depends on carboxylesterases and formation of lysosome-related organelles. Henry H Le, Chester JJ Wrobel, Sarah M Cohen, Jingfang Yu, Heenam Park, Maximilian J Helf, Brian J Curtis, Joseph C Kruempel, Pedro Reis Rodrigues, Patrick J Hu, Paul W Sternberg, Frank C Schroeder, eLife. 2020, 9, e61886. doi: 10.7554/eLife.61886
159. Deep Interrogation of Metabolism Using a Pathway-Targeted Click-Chemistry Approach. Jason S Hoki, Henry H Le, Karlie E Mellott, Ying K Zhang, Bennett W Fox, Pedro R Rodrigues, Yan Yu, Maximilian J Helf, Joshua A Baccile, Frank C Schroeder, J. Am. Chem. Soc. 2020, 142, 18449-18459. doi: 10.1021/jacs.0c06877
158. Modeling tissue-relevant Caenorhabditis elegans metabolism at network, pathway, reaction, and metabolite levels. Lutfu Safak Yilmaz, Xuhang Li, Shivani Nanda, Bennett Fox, Frank Schroeder, Albertha JM Walhout, Mol Syst Biol. 2020, 16, e9649. doi: 10.15252/msb.20209649
157. Toward spatially resolved metabolomics. Bennett W Fox, Frank C Schroeder, Nature Chemical Biology. 2020, 16, 1039-1040. doi: 10.1038/s41589-020-00650-0
156. Identification of Uric Acid Gluconucleoside-Ascaroside Conjugates in Caenorhabditis elegans by Combining Synthesis and MicroED. Brian J Curtis, Lee Joon Kim, Chester JJ Wrobel, James M Eagan, Rubin A Smith, Jessica E Burch, Henry H Le, Alexander B Artyukhin, Hosea M Nelson, Frank C Schroeder, Org. Lett. 2020, 22, 6724-6728. doi: 10.1021/acs.orglett.0c02038.s001
155. A neurotransmitter produced by gut bacteria modulates host sensory behaviour. Michael P O’Donnell, Bennett W Fox, Pin-Hao Chao, Frank C Schroeder, Piali Sengupta, Nature. 2020, 1-6. doi: 10.1038/s41586-020-2395-5
154. Population Density Modulates the Duration of Reproduction of C. elegans. Spencer S Wong, Jingfang Yu, Frank C Schroeder, Dennis H Kim, Current Biology. 2020, 30, 1-6. doi: 10.1016/j.cub.2020.04.056
153. Plant metabolism of nematode pheromones mediates plant-nematode interactions. Murli Manohar, Francisco Tenjo-Castano, Shiyan Chen, Ying K Zhang, Anshu Kumari, Valerie M Williamson, Xiaohong Wang, Daniel F Klessig, Frank C Schroeder, Nature Communications. 2020, 11, 208. doi: 10.1038/s41467-019-14104-2
152. Photoaffinity probes for nematode pheromone receptor identification. Ying K Zhang, Douglas K Reilly, Jingfang Yu, Jagan Srinivasan, Frank C Schroeder, Org. Biomol. Chem. 2020, 18, 36-40. doi: 10.1039/C9OB02099C
151. Intestinal peroxisomal fatty acid β-oxidation regulates neural serotonin signaling through a feedback mechanism. Aude D Bouagnon, Lin Lin, Shubhi Srivastava, Chung-Chih Liu, Oishika Panda, Frank C Schroeder, Supriya Srinivasan, Kaveh Ashrafi, PLoS Biology. 2019, 17, e3000242. doi: 10.1101/602649
150. The microbiota regulate neuronal function and fear extinction learning. Coco Chu, Mitchell H Murdock, Deqiang Jing, Tae Hyung Won, Hattie Chung, Adam M Kressel, Tea Tsaava, Meghan E Addorisio, Gregory G Putzel, Lei Zhou, Nicholas J Bessman, Ruirong Yang, Saya Moriyama, Christopher N Parkhurst, Anfei Li, Heidi C Meyer, Fei Teng, Sangeeta S Chavan, Kevin J Tracey, Aviv Regev, Frank C Schroeder, Francis S Lee, Conor Liston, David Artis, Nature. 2019, 547, 543-548. doi: 10.1038/s41586-019-1644-y
149. Diketopiperazine Formation in Fungi Requires Dedicated Cyclization and Thiolation Domains. Joshua A. Baccile, Henry H. Le, Brandon T. Pfannenstiel, Jin Woo Bok, Christian Gomez, Eileen Brandenburger, Dirk Hoffmeister, Nancy P. Keller, Frank C. Schroeder, Angewandte Chemie International Edition. 2019, 58, 1-6. doi: 10.1002/anie.201909052
148. An excreted small molecule promotes C. elegans reproductive development and aging. Andreas H. Ludewig, Alexander B. Artyukhin, Erin Z. Aprison, Pedro R. Rodrigues, Dania C. Pulido, Russell N. Burkhardt, Oishika Panda, Ying K. Zhang, Pooja Gudibanda, Ilya Ruvinsky, Frank C. Schroeder, Nature Chemical Biology. 2019, 15, 838-845. doi: 10.1038/s41589-019-0321-7
147. Co-option of neurotransmitter signaling for inter-organismal communication in C. elegans. Christopher D Chute, Elizabeth M DiLoreto, Ying K Zhang, Douglas K Reilly, Diego Rayes, Veronica L Coyle, Hee June Choi, Mark J Alkema, Frank C Schroeder, Jagan Srinivasan, Nature Communications. 2019, 10, 3186. doi: 10.1101/275693
146. Nematode ascaroside enhances resistance in a broad spectrum of plant-pathogen systems. Daniel F Klessig, Murli Manohar, Shine Baby, Aline Koch, Wiseborn B Danquah, Emily Luna, Hee-Jin Park, Judith M Kolkman, B Gillian Turgeon, Rebecca Nelson, Jan E Leach, Valerie M Williamson, Karl-Heinz Kogel, Aardra Kachroo, Frank C Schroeder, Journal of Phytopathology. 2019, 167, 265-272. doi: 10.1111/jph.12795
145. Metabolome-scale genome-wide association studies reveal chemical diversity and genetic control of maize specialized metabolites. Shaoqun Zhou, Karl A Kremling, Nonoy Bandillo, Annett Richter, Ying K Zhang, Kevin R Ahern, Alexander B Artyukhin, Joshua X Hui, Gordon C Younkin, Frank C Schroeder, Edward S Buckler, Georg Jander, The Plant Cell. 2019, 31, 937-955. doi: 10.1101/450338
144. Natural variation in C. elegans arsenic toxicity is explained by differences in branched chain amino acid metabolism. Stefan Zdraljevic, Bennett William Fox, Christine Strand, Oishika Panda, Francisco J Tenjo, Shannon C Brady, Tim A Crombie, John G Doench, Frank C Schroeder, Erik C Andersen, Elife. 2019, 8, e40260. doi: 10.7554/elife.40260
143. Ethylene signaling regulates natural variation in the abundance of antifungal acetylated diferuloylsucroses and Fusarium graminearum resistance in maize seedling roots. Shaoqun Zhou, Ying K Zhang, Karl A Kremling, Yezhang Ding, John S Bennett, Justin S Bae, Dean K Kim, Hayley H Ackerman, Michael V Kolomiets, Eric A Schmelz, Frank C Schroeder, Edward S Buckler, Georg Jander, New Phytologist. 2019, 221, 2096-2111. doi: 10.1111/nph.15520
142. Phevamine A, a small molecule that suppresses plant immune responses. Erinn M O’Neill, Tatiana S Mucyn, Jon B Patteson, Omri M Finkel, Eui-Hwan Chung, Joshua A Baccile, Elisabetta Massolo, Frank C Schroeder, Jeffery L Dangl, Bo Li, PNAS. 2018, 115, E9514-E9522. doi: 10.1073/pnas.1803779115
141. Biology and genome of a newly discovered sibling species of Caenorhabditis elegans. Natsumi Kanzaki, Isheng J Tsai, Ryusei Tanaka, Vicky L Hunt, Dang Liu, Kenji Tsuyama, Yasunobu Maeda, Satoshi Namai, Ryohei Kumagai, Alan Tracey, Nancy Holroyd, Stephen R Doyle, Gavin C Woodruff, Kazunori Murase, Hiromi Kitazume, Cynthia Chai, Allison Akagi, Oishika Panda, Huei-Mien Ke, Frank C Schroeder, John Wang, Matthew Berriman, Paul W Sternberg, Asako Sugimoto, Taisei Kikuchi, Nature communications. 2018, 9, 3216. doi: 10.1038/s41467-018-05712-5
140. Fungal isocyanide synthases and xanthocillin biosynthesis in Aspergillus fumigatus. Fang Yun Lim, Tae Hyung Won, Nicholas Raffa, Joshua A Baccile, Jen Wisecaver, Antonis Rokas, Frank C Schroeder, Nancy P Keller, mBio. 2018, 9, e00785-18. doi: 10.1128%2Fmbio.00785-18
139. Conserved Responses in a War of Small Molecules between a Plant-Pathogenic Bacterium and Fungi. Joseph E Spraker, Philipp Wiemann, Joshua A Baccile, Nandhitha Venkatesh, Julia Schumacher, Frank C Schroeder, Laura M Sanchez, Nancy P Keller, mBio. 2018, 9, e00820-18. doi: 10.1128/mbio.00820-18
138. Linking genomic and metabolomic natural variation uncovers nematode pheromone biosynthesis. Jan M Falcke, Neelanjan Bose, Alexander B Artyukhin, Christian Rödelsperger, Gabriel V Markov, Joshua J Yim, Dominik Grimm, Marc H Claassen, Oishika Panda, Joshua A Baccile, Ying K Zhang, Henry H Le, Dino Jolic, Frank C Schroeder, Ralf J Sommer, Cell Chemical Biology. 2018, 25, 787-796. doi: 10.1016/j.chembiol.2018.04.004
137. Predator-secreted sulfolipids induce defensive responses in C. elegans. Zheng Liu, Maro J Kariya, Christopher D Chute, Amy K Pribadi, Sarah G Leinwand, Ada Tong, Kevin P Curran, Neelanjan Bose, Frank C Schroeder, Jagan Srinivasan, Sreekanth H Chalasani, Nature communications. 2018, 9, 1228. doi: 10.1038/s41467-018-03333-6
136. Metabolomic "Dark Matter" Dependent on Peroxisomal β-Oxidation in Caenorhabditis elegans. Alexander B Artyukhin, Ying K Zhang, Allison E Akagi, Oishika Panda, Paul W Sternberg, Frank C Schroeder, J. Am. Chem. Soc. 2018, 140, 2841-2852. doi: 10.1021/jacs.7b11811
135. Modeling meets metabolomics–the wormjam consensus model as basis for metabolic studies in the model organism Caenorhabditis elegans. Michael Anton Witting, Janna Hastings, Nicolas Rodriguez, Chintan Joshi, Jake Hattwell, Paul Ebert, Michel van Weeghel, Arwen Gao, Michael Wakelam, Riekelt Houtkooper, Abraham Mains, Nicolas Le Novère, Sean Sadykoff, Frank Schroeder, Nathan Lewis, Horst-Joachim Schirra, Christoph Kaleta, Olivia Casanueva, Front. Mol. Biosci. 2018, 5, 96. doi: 10.3389/fmolb.2018.00096
134. Improved Synthesis for Modular Ascarosides Uncovers Biological Activity. Zhang YK, Sanchez-Ayala MA, Sternberg PW, Srinivasan J, Schroeder FC, Org. Lett. 2017, 19, 2837-2840. doi: 10.1021/acs.orglett.7b01009
133. Larval crowding accelerates C. elegans development and reduces lifespan. Ludewig AH, Gimond C, Judkins JC, Thornton S, Pulido DC, Micikas RJ, Döring F, Antebi A, Braendle C, Schroeder FC, PLoS Genetics 2017, 13, e1006717. doi: 10.1371/journal.pgen.1006717
132. Biosynthesis of Modular Ascarosides in C. elegans. Oishika Panda, Allison E. Akagi, Dr. Alexander B. Artyukhin, Dr. Joshua C. Judkins, Henry H. Le, Dr. Parag Mahanti, Sarah M. Cohen, Prof. Paul W. Sternberg, Prof. Frank C. Schroeder, Angew. Chem. Int. Ed. Engl. 2017, 56, 4729-4733. doi: 10.1002/anie.201700103
131. Molecular Determinants of the Regulation of Development and Metabolism by Neuronal eIF2? Phosphorylation in Caenorhabditis elegans. Kulalert W, Sadeeshkumar H, Zhang YK, Schroeder FC, Kim DH, Genetics 2017, 206, 251-263. doi: 10.1534/genetics.117.200568
130. Nematophagous fungus Arthrobotrys oligospora mimics olfactory cues of sex and food to lure its nematode prey. Yen-Ping Hsueh Matthew R Gronquist Erich M Schwarz Ravi David Nath Ching-Han Lee Shalha Gharib Frank C Schroeder Paul W Sternberg, eLIFE 2017, 6, e20023. doi: 10.7554/eLife.20023
129. Elucidating the Rimosamide-Detoxin Natural Product Families and Their Biosynthesis Using Metabolite/Gene Cluster Correlations. Ryan A. McClure, Anthony W. Goering, Kou-San Ju, Joshua A. Baccile, Frank C. Schroeder, William W. Metcalf, Regan J. Thomson, and Neil. L Kelleher, ACS Chem. Biol. 2016, 11, 3452-3460. doi: 10.1021/acschembio.6b00779
128. Tomato receptor FLAGELLIN-SENSING 3 binds flgII-28 and activates the plant immune system. Sarah R. Hind, Susan R. Strickler, Patrick C. Boyle, Diane M. Dunham, Zhilong Bao, Inish M. O'Doherty, Joshua A. Baccile, Jason S. Hoki, Elise G. Viox, Christopher R. Clarke, Boris A. Vinatzer, Frank C. Schroeder & Gregory B. Martin, Nat. Plants 2016, 2, 16128. doi: 10.1038/nplants.2016.128
127. Plant-like biosynthesis of isoquinoline alkaloids in Aspergillus fumigatus. Joshua A. Baccile, Joseph E. Spraker, Henry H. Le, Eileen Brandenburger, Christian Gomez, Jin Woo Bok, Juliane Macheleidt, Axel A. Brakhage, Dirk Hoffmeister, Nancy P. Keller, Frank C. Schroeder, Nat. Chem. Biol. 2016, 12, 419-424. doi: 10.1038/nchembio.2061
126. Contrasting responses within a single neuron class enable sex-specific attraction in Caenorhabditis elegans. Anusha Narayan, Vivek Venkatachalam, Omer Durak, Douglas K. Reilly, Neelanjan Bose, Frank C. Schroeder, Aravinthan D. T. Samuel, Jagan Srinivasan, Paul W. Sternberg, Proc. Natl. Acad. Sci. USA 2016, 33, E1392-E1401. doi: 10.1073/pnas.1600786113
125. BLIMP-1/BLMP-1 and Metastasis-Associated Protein Regulate Stress Resistant Development in Caenorhabditis elegans. Anusha Hyun M, Kim J, Dumur C, Schroeder FC, You YJ, Genetics 2016, 203, 1721-1732. 10.1534/genetics.116.190793
124. Functional Conservation and Divergence of daf-22 Paralogs in Pristionchus pacificus Dauer Development. Markov GV, Meyer JM, Panda O, Artyukhin AB, Claaßen M, Witte H, Schroeder FC, Sommer RJ, Mol. Biol. Evol. 2016, 113, 2506-2514. doi: 10.1093/molbev/msw090
123. Amorfrutin C Induces Apoptosis and Inhibits Proliferation in Colon Cancer Cells through Targeting Mitochondria. Christopher Weidner, Morten Rousseau, Robert J. Micikas, Cornelius Fischer, Annabell Plauth, Sylvia J. Wowro, Karsten Siems, Gregor Hetterling, Magdalena Kliem, Frank C. Schroeder, Sascha Sauer, J. Nat. Prod. 2016, 79, 2-12. doi: 10.1021/acs.jnatprod.5b00072
122. Conserved nematode signalling molecules elicit plant defenses and pathogen resistance. Patricia Manosalva, Murli Manohar, Stephan H. von Reuss, Shiyan Chen, Aline Koch, Fatma Kaplan, Andrea Choe, Robert J. Micikas, Xiaohong Wang, Karl-Heinz Kogel, Paul W. Sternberg, Valerie M. Williamson, Frank C. Schroeder & Daniel F. Klessig, Nat. Comm. 2015, 6, 7795. doi: 10.1038/ncomms8795
121. Aspirin's Active Metabolite Salicylic Acid Targets High Mobility Group Box 1 to Modulate Inflammatory Responses. Hyong Woo Choi, Miaoying Tian, Fei Song, Emilie Venereau, Alessandro Preti, Sang-Wook Park, Keith Hamilton, G. V. T. Swapna, Murli Manohar, Magali Moreau, Alessandra Agresti, Andrea Gorzanelli, Francesco De Marchis, Huang Wang, Marc Antonyak, Robert J. Micikas, Daniel R. Gentile, Richard A. Cerione, Frank C. Schroeder, Gaetano T. Montelione, Marco E. Bianchi, Daniel F. Klessig, Mol. Med. 2015, 21, 526-535. doi: 10.2119/molmed.2015.00148
120. Chemoenzymatic synthesis of thiazolyl peptide natural products featuring an enzyme-catalyzed formal [4 + 2] cycloaddition. Walter J. Wever, Jonathan W. Bogart, Joshua A. Baccile, Andrew N. Chan, Frank C. Schroeder, Albert A. Bowers, J. Am. Chem. Soc. 2015, 137, 3494-3497.doi: 10.1021/jacs.5b00940
119. Combinatorial chemistry in nematodes: modular assembly of primary metabolism-derived building blocks. Stephan. H. von Reuss, Frank C. Schroeder, Nat. Prod. Rep. 2015, 32, 994-1006.dx.doi.org/10.1039/c5np00042d
118. Modular Assembly of Primary Metabolic Building Blocks: A Chemical Language in C. elegans. Frank C. Schroeder, Chem. Biol. 2015, 22, 7-16. doi:10.1016/j.chembiol.2014.10.012
117. B. subtilis GS67 protects C. elegans from Gram-positive pathogens via fengycin-mediated microbial antagonism. Igor Iatsenko, Joshua J. Yim, Frank C. Schroeder, Ralf J. Sommer, Curr. Biol. 2014, 24, 2720-2727.
116. Perturbations in small molecule synthesis uncovers an iron-responsive secondary metabolite network in Aspergillus fumigatus. Philipp Wiemann, Beatrix E. Lechner, Joshua A. Baccile, Thomas A. Velk, Wen-Bing Yin, Jin Woo Bok, Suman Pakala, Liliana Losada, William C. Nierman, Frank C. Schroeder, Hubertus Haas, Nancy P. Keller. Front. Microbiol. 2014, 5, 530.
115. Chemosensation of Bacterial Secondary Metabolites Modulates Neuroendocrine Signaling and Behavior of C. elegans. Joshua D. Meisel, Oishika Panda, Parag Mahanti, Frank C. Schroeder, Dennis H. Kim. Cell 2014, 159, 267-280. doi:10.1016/j.cell.2014.09.011
114. Activation of a G protein-coupled receptor by its endogenous ligand triggers the innate immune response of Caenorhabditis elegans. Olivier Zugasti, Neelanjan Bose, Barbara Squiban, Jérôme Belougne, C. Léopold Kurz, Frank C. Schroeder, Nathalie Pujol, Jonathan J. Ewbank. Nat. Immunol. 2014, 15, 833-838. doi:10.1016/j.cub.2014.05.045
113. Small molecule signaling: encoding biological information in chemical structures. Frank C. Schroeder. In "Pristionchus pacificus - A nematode model for comparative and evolutionary biology", edited by Ralf J. Sommer. Brill, Leiden, NL, 2014, in press.
112. Endogenous NHR ligands: metabolomics to the rescue. Axel Bethke, Frank C. Schroeder. Aging, 2014, 6, 522-523. Editorial
111. Natural variation in dauer pheromone production and sensing supports intraspecific competition in nematodes. . Neelanjan Bose, Jan M. Meyer, Joshua J. Yim, Melanie G. Mayer, Gabriel V. Markov, Akira Ogawa, Frank C. Schroeder, Ralf J. Sommer. Curr. Biol. 2014, 24, 1536-1541. doi:10.1016/j.cub.2014.05.045
110. A Photocleavable Masked Nuclear-Receptor Ligand Enables Temporal Control of C. elegans Development. Joshua C. Judkins, Parag Mahanti, Jacob B. Hoffman, Isaiah Yim, Adam Antebi, Frank C. Schroeder. Angew. Chem. Int. Ed., 2014, 53, 2110-2113. DOI:10.1002/anie.201307465
Highlighted as a Hot Paper by Angewandte Chemie
109. Males Shorten the Life Span of C. elegans Hermaphrodites via Secreted Compounds. Travis J. Maures, Lauren N. Booth, Berenice A. Benayoun, Yevgeniy Izrayelit, Frank C. Schroeder, Anne Brunet. Science, 2014, 343, 541-544. DOI:10.1126/science.1244160
Highlighted in The New York Times, Science Daily, National Geographic Phenomena, GEN, Nature World News
108. Comparative Metabolomics Reveals Endogenous Ligands of DAF-12, a Nuclear Hormone Receptor, Regulating C. elegans Development and Lifespan. Parag Mahanti, Neelanjan Bose. Axel Bethke, Joshua C. Judkins, Joshua Wollam, Kathleen J. Dumas, Anna M. Zimmerman, Sydney L. Campbell, Patrick J. Hu, Adam Antebi, Frank C. Schroeder. Cell Metab., 2014, 19, 73-83. DOI:10.1016/j.cmet.2013.11.024
107. Density dependence in Caenorhabditis larval starvation. Alexander B. Artyukhin, Frank C. Schroeder, Leon Avery.Scientific Reports, 2013, 19, 73-83.DOI:10.1016/j.cmet.2013.11.024
106. Anthranilate fluorescence marks a calcium-propagated necrotic wave that promotes organismal death in C. elegans. Cassandra Coburn, Erik Allman, Parag Mahanti, Alexandre Benedetto, Filipe Cabreiro, Zachary Pincus, Filip Matthijssens, Caroline Araiz, Abraham Mandel, Manolis Vlachos, Sally-Anne Edwards, Grahame Fischer, Alexander Davidson, Rosina E. Pryor, Ailsa Stevens, Frank J. Slack, Nektarios Tavernarakis, Bart P. Braeckman, Frank C. Schroeder, Keith Nehrke, David Gems. PLoS Biol., 2013, 11, e1001613. DOI:10.1371/journal.pbio.1001613
Highlighted in Science Daily, TheScientist, F1000
105. Succinylated octopamine ascarosides and a new pathway of biogenic amine metabolism in Caenorhabditis elegans. Alexander B. Artyukhin, Joshua J. Yim, Jagan Srinivasan, Neelanjan Bose, Stephan H. von Reuss, Yeara Jo, James M. Jordan, L. Ryan Bough, Micheong Cheong, Paul W. Sternberg, Leon Avery, Frank C. Schroeder. J. Biol. Chem., 2013, 288, 18778-18783. DOI:10.1074/jbc.C113.477000
104. Chemical defense of an Asian snake reflects local availability of toxic prey and hatchling diet. Deborah A. Hutchinson, Alan Savitzky, Gordon M. Burghardt, C. Nguyen, Jerrold Meinwald, Frank C. Schroeder, Akira Mori. J. Zool., 2013, 289, 270-278. DOI:10.1111/jzo.12004
103. Amorfrutin B is an efficient natural peroxisome proliferator-activated receptor gamma (PPARγ) agonist with potent glucose-lowering properties. Christopher Weidner, S.J. Wowro, Freiwald A, Ken Kawamoto, A. Witzke, M. Kliem, K. Siems, L. Müller-Kuhrt, Frank C. Schroeder, Sascha Sauer. Diabetologia, 2013, 56, 1802-1812. DOI 10.1007/s00125-013-2920-2
102. Protein sets define disease states and predict in vivo effects of drug treatment. David Meierhofer, Christopher Weidner, Ludger Hartmann, Johannes A. Mayr, Chung-Ting Han, Frank C. Schroeder, Sascha Sauer. Mol. Cell. Proteomics, 2013, 7, 1965-1979. DOI:10.1074/mcp.M112.025031
101.Pheremone sensing regulate Caenorhabditis elegans lifepsan and stress resistance via the deacetylase SIR-2.1. Andreas H. Ludewig, Yevgeniy Izrayelit, Donha Park, Rabia U. Malik, Anna Zimmerman, Parag Mahanti, Bennett W. Fox, Axel Bethke, Frank Doering, Donald L. Riddle, Frank C. Schroeder. Proc. Natl. Acad. Sci. USA, 2013, 110, 5522-5527. DOI:10.1073/pnas.1214467110
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100. A Nonribosomal Peptide Synthetase-Derived Iron(III) Complex from the Pathogenic Fungus Aspergillus fumigatus. Wen-Bing Yin, Joshua A. Baccile, Jin Woo Bok, Yiming Chen, Nancy P. Keller, Frank C. Schroeder.J. Am. Chem. Soc., 2013, 135, 2064-2067. DOI:10.1021/ja311145n
99. A Family of Indoles Regulate Virulence and Shiga Toxin Production in Pathogenic E. coli. Bettina Bommarius, Akwasi Anyanful, Yevgeniy Izrayelit, Shantanu Bhatt, Emily Cartwright, Wei Wang, Alyson I. Swimm, Guy M. Benian, Frank C. Schroeder, Daniel Kalman.PLoS ONE, 2013, 8, e54456. DOI:10.1371/journal.pone.0054456
98. Ascaroside signaling in C. elegans. Andreas H. Ludewig, Frank C. Schroeder. WormBook 2013, 1- 22. DOI:10.1895/wormbook.1.155.1
97. Structural Characterization of Amorfruitins Bound to the Peroxisome Proliferator-Activated receptor γ. Jens C. de Groot, Christopher Wiedner, Joern Krausze, Ken Kawamoto, Frank C. Schroeder, Sascha Sauer, Kondrad Bussow. J. Med. Chem. 2013, 56, 1535-1543 DOI:10.1021/jm3013272
96. Nematode-Trapping Fungi Eavesdrop on Nematode Pheromones. Yen-Ping Hsueh, Parag Mahanti, Frank C. Schroeder, Paul W. Sternberg. Current Biology. 2013, 7, 83-86 DOI.10.1016/j.cub.2012.11.035
Highlighted in Science Daily, National Geographic Phenomena
95. 2D NMR-based metabolomics uncovers interactions between conserved biochemical pathways in the model organism Caenorhabditis elegans. Yevgeniy Izrayelit, Steven L. Robinette, Neelanjan Bose, Stephan H. von Reuss, Frank C. Schroeder. ACS Chem. Biol., 2013, 8, 314-319 DOI:10.1021/cb3004644
94. Chemical detoxification of small molecules by C. elegans. Gregory S. Stupp, Stephan H. von Reuss, Yevgeniy Izrayelit, Ramadan Ajredini, Frank C. Schroeder, Arthur S. Edison. ACS Chem. Biol., 2013, 8, 309-313 DOI:10.1021/cb300520u
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93. Homologous NRPS-like Gene Clusters Mediate Redundant Small-Molecule Biosynthesis in Aspergillus flavus. Ry. R. Forseth, Saori Amaike, Daniel Schwenk, Katharyn J. Affeldt, Dirk Hoffmeister, Frank C. Schroeder, Nancy P. Keller. Angew. Chem. Int. Ed., 2012, 52, 1590-1594 DOI:10.1002/anie.201207456
92. Sex-specific mating pheromones in the nematode Panagrellus redivivus. Andrea Chose, Tatsuji Chuman, Stephan H. von Reuss, Aaron T. Dossey, Joshua J. Yim, Ramadan Ajredini, Adam A. Kolawa, Fatma Kaplan, Hans T. Alborn, Peter E. A. Teal, Frank C. Schroeder, Paul W. Sternberg, Arthur S. Edison.Proc. Natl. Acad. Sci. USA 2012, 109, 20949-20954. DOI:10.1073/pnas.1218302109
91. Complex Small-Molecule Architectures Regulate Phenotypic Plasticity in a Nematode. Neelanjan Bose, Akira Ogawa, Stephan H. von Reuss, Joshua J. Yim, Erik J. Ragsdale, Ralf J. Sommer, Frank C. Schroeder. Angew. Chem. Int. Ed., 2012, 51, 12438-12443 DOI:10.1002/anie.201206797
90. A Backup Plan for Self-Protection: S-Methylation of Holomycin Biosynthetic intermediates in Streptomyces clavuligerus. Bo Li, Ry R. Forseth, Albert A. Bowers, Frank C. Schroeder, Christopher T. Walsh. ChemBioChem, 2012, 13, 2521-2526 DOI:10.1002/cbic.201200536
89. Correlating Secondary Metabolite Production with Genetic Changes Using Differential Analysis of 2D NMR Spectra. Ry R. Forseth, Frank C. Schroeder. Methods Mol. Biol, 2012, 944, 207-219 DOI: 10.1007/978-1-62703-122-6_15
88. Interspecific Nematode Signals Regulate Dispersal Behavior. Fatma Kaplan, Hans T. Alborn, Stephan H. von Reuss, Ramadan Ajredini, Jared G. Ali, Faruk Akyazi, Lukasz L. Stelinski, Arthur S. Edison, Frank C. Schroeder, Peter E. Teal. PLoS ONE, 2012, 7, e387635 DOI:10.1371/journal.pone.0038735
87. Interaction of structure-specific and promiscuous G-protein–coupled receptors mediates small-molecule signaling in Caenorhabditis elegans. Donha Park, Inish O’Doherty, Rishi K. Somvanshi, Axel Bethke, Frank C. Schroeder, Ujendra Kumar, and Donald L. Riddle. Proc. Natl. Acad. Sci. USA 2012, 109, 9917-9922. DOI:10.1073/pnas.1202216109
86. Targeted Metabolomics Reveals a Male Pheromone and Sex-Specific Ascaroside Biosynthesis in Caenorhabditis elegans. Yevgeniy Izrayelit, Jagan Srinivasan, Sydney L. Campbell, Yeara Jo, Stephan H. von Reuss, Margaux C. Genoff, Paul W. Sternberg, and Frank C. Schroeder. ACS Chem. Biol. 2012, 7, 1321-1325. DOI:10.1021/cb300169c
85. Amorfrutins are potent antidiabetic dietary natural products. Christopher Weidner, Jens C. de Groot, Aman Prasad, Anja Freiwald, Claudia Quedenau, Magdalena Kliem, Annabell Witzke, Vitam Kodelja, Chung-Ting Han, Sascha Giegold, Matthias Baumann, Bert Klebl, Karsten Siems, Lutz Müller-Kuhrt, Annette Schürmann, Rita Schüler, Andreas F. H. Pfeiffer, Frank C. Schroeder, Konrad Büssow, and Sascha Sauer. Proc. Natl. Acad. Sci. USA 2012, 109, 7257-7262.DOI:10.1073/pnas.1116971109
84. Steroids as Central Regulators of Organismal Development and Lifespan. Siu Sylvia Lee and Frank C. Schroeder. PLoS Biology, 2012, 10, e1001307. DOI:10.1371/journal.pbio.1001307
83. Ascaroside Signaling Is Widely Conserved among Nematodes. Andrea Choe, Stephan H. von Reuss, Dima Kogan, Robin B. Gasser, Edward G. Platzer, Frank C. Schroeder, Paul W. Sternberg. Current Biology, 2012, 22, R294-R296. DOI:10.1016/j.cub.2012.03.024
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82. A Modular Library of Small Molecule Signals Regulates Social Behaviors in Caenorhabditis elegans. Jagan Srinivasan, Stephan H. von Reuss, Neelanjan Bose, Alon Zaslaver, Parag Mahanti, Margaret C. Ho, Oran G. O'Doherty, Arthur S. Edison, Paul W. Sternberg, Frank C. Schroeder. PLoS Biology, 2012, 10, e1001237. DOI:10.1371/journal.pbio.1001237
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81. Comparative Metabolomics Reveals Biogenesis of Ascarosides, a Modular Library of Small-Molecule Signals in C. elegans. Stephan H. von Reuss, Neelanjan Bose, Jagan Srinivasan, Joshua J. Yim, Joshua C. Judkins, Paul W. Sternberg, and Frank C. Schroeder. J. Am. Chem. Soc., 2012, 134, 1817-1824. DOI:10.1021/ja210202y
80. Synthesis of caeliferins, elicitors of plant immune responses: accessing lipophilic natural products via cross metathesis. Inish O’Doherty, Joshua J. Yim, Eric A. Schmelz, and Frank C. Schroeder. Org. Lett., 2011, 13, 5900–5903 DOI:10.1021/ol202541b
79. Microfluidic chamber arrays for whole-organism behavior-based chemical screening. Kwanghun Chung, Mei Zhan, Jagan Srinivasan, Paul W. Sternberg, Emily Gong, Frank C. Schroeder and Hang Lu. Lab Chip, 2011, 11, 3689-3697. DOI: 10.1039/c1lc20400a
78. Scents of adolescence: the maturation of the olfactory phenotype in a free-ranging mammal. Barbara A. Caspers, Frank C. Schroeder, Stephan Franke, Christian C. Voigt, PLoS One 2011, 6, e21162. DOI: 10.1371/journal.pone.0021162
77. NMR in Metabolomics and Natural Products Research: Two Sides of the Same Coin. Steven L. Robinette, Rafael Bru¨schweiler, Frank C. Schroeder, Arthur S. Edison, Acc. Chem. Res. 2011, 45, 288-297. DOI:10.1021/ar2001606
76. Biosynthetic Chlorination of the Piperazate Residue in Kutzneride Biosynthesis by KthP. Wei Jiang, John R. Heemstra, Jr, Ry R. Forseth, Christopher S. Neumann, Soraya Manaviazar, Frank C. Schroeder, Karl J. Hale, Christopher T. Walsh, Biochemistry 2011, 50, 6063-6072. DOI: 10.1021/bi200656k
75. 2D NMR-spectroscopic screening reveals polyketides in ladybugs. Stephen T. Deyrup, Laura E. Eckman, Patrick H. McCarthy, Scott R. Smedley, Jerrold Meinwald, and Frank C. Schroeder, Proc. Natl. Acad. Sci. USA 2011, 108, 9753-9758.DOI: 10.1073/pnas.1107020108.
74. Identification of Cryptic Products of the Gliotoxin Gene Cluster using NMR-based Comparative Metabolomics and a Model for Gliotoxin Biosynthesis. Ry R. Forseth, Ellen M. Fox, DaWoon Chung, Barbara J. Howlett, Nancy P. Keller, Frank C. Schroeder, J. Am. Chem. Soc. 2011, 133, 9678-9681. DOI: 10.1021/ja2029987.
73. Chemical investigations of defensive steroid sequestration by the Asian snake Rhabdophis tigrinus. Deborah A. Hutchinson, Alan H. Savitzky, Akira Mori, Gordon M. Burghardt, Jerrold Meinwald, Frank C. Schroeder, Chemoecology 2012, 3, 199-206. DOI 10.1007/s00049-011-0078-2.
72. Ascaroside Expression in Caenorhabditis elegans is Strongly Dependent on Diet and Developmental Stage. Fatma Kaplan, Jagan Srinivasan, Parag Mahanti, Ramadan Ajredini, Omer Durak, Rathika Nimalendran, P. W. Sternberg, Peter E. A. Teal, Frank C. Schroeder, Arthur S. Edison, Hans T. Alborn, PLoS ONE 2011, 6: e17804. DOI:10.1371/journal.pone.0017804.
71. Spirocyclic Lignans from Guaiacum (Zygophyllaceae) Induce Apoptosis in Human Breast Cancer Cell Lines. Kathryn J. Chavez, Xiaohong Feng, James A. Flanders, Eloy Rodriguez, Frank C. Schroeder, J. Nat. Prod. 2011, 74, 1293-1297. DOI: 10.1021/np100891y.
70. Hierarchical Alignment and Full Resolution Pattern Recognition of 2D NMR Spectra: Application to Nematode Chemical Ecology. Steven L. Robinette, Ramadan Ajredini, Hasan Rasheed, Abdulrahman Zeinomar, Frank C. Schroeder, Aaron T. Dossey, Arthur S. Edison. Anal Chem. 2011, 83, 1649–1657. DOI: 10.1021/ac102724x
69. NMR-spectroscopic analysis of mixtures: from structure to function. Ry R. Forseth, Frank C. Schroeder. Curr. Opin. Chem. Biol. 2011, 15, 38-47. DOI:10.1016/j.cbpa.2010.10.010.
68. Highly a-selective hydrolysis of a,ß-epoxyalcohols using tetrabutylammonium fluoride. Purba Mukerjee, Mohammed Abid, Frank C. Schroeder. Org. Lett. 2010, 12, 3986–3989. DOI:10.1021/ol1015306.
67. NMR – Small Molecules and Analysis of Complex Mixtures. Arthur Edison, Frank C. Schroeder. Review. In: Comprehensive Natural Products Chemistry II Eds. Lew Mander, Hung-Wen Liu, Elsevier 2010, Vol. 9, pp 169-196. http://dx.doi.org/10.1016/B978-008045382-8.00196-9.
66. Insect Natural Products. Matthew Gronquist, Frank C. Schroeder. Review. In: Comprehensive Natural Products Chemistry II Eds. Lew Mander, Hung-Wen Liu, Elsevier 2010, Vol. 2, pp. 67-108. http://dx.doi.org/10.1016/B978-008045382-8.00035-6.
65. A shortcut to identifying small molecule signals that regulate behavior and development in Caenorhabditis elegans. Chirag Pungaliya, Jagan Srinivasan, Bennett W. Fox, Rabia U. Malik, Andreas H. Ludewig, Paul W. Sternberg, Frank C. Schroeder. Proc. Natl. Acad. Sci. USA 2009, 106, 7708-7713. [PMCID: PMC2683085], doi:10.1073/pnas.0811918106.
This paper was highlighted in "DANSing with Caenorhabditis elegans". Patrick J. Hu, David H. Sherman, Proc. Natl. Acad. Sci. USA 2009, 106, 7685-7686.
64. NMR-spectroscopic screening of spider venom reveals sulfated nucleosides as major components for the brown recluse and related species. Frank C. Schroeder, Andrew E. Taggi, Matthew Gronquist, Rabia U. Malik, Jacqualine B. Grant, Thomas Eisner, Jerrold Meinwald. Proc. Natl. Acad. Sci. USA 2008, 105, 14283-14287.
63. Biosynthesis of the thiamin-thiazole in eukaryotes: identification of a thiazole tautomer intermediate. Abhishek Chatterjee, Frank C. Schroeder, Christopher T. Jurgenson, Steven E. Ealick, Tadhg P. Begley. J. Am. Chem. Soc. 2008, 130, 11394-11398.
62. A blend of small molecules regulates both mating and development in Caenorhabditis elegans. Jagan Srinivasan, Fatma Kaplan, Ramazan Ajredini, Cherian Zachariah, Hans Alborn, Peter Teal, Rabia U. Malik, Arthur S. Edison, Paul W. Sternberg, Frank C. Schroeder, Nature, 2008, 454, 1115-1118.
61. Defensive chemistry of lycid beetles and of mimetic cerambycid beetles that feed on them. Thomas Eisner, Frank C. Schroeder, Noel Snyder, Jacqualine B. Grant, Daniel J. Aneshansley, David Utterback, Jerrold Meinwald and Maria Eisner. Chemoecology 2008, 18, 109-119.
60. Maternal provisioning of sequestered defensive steroids by the Asian snake Rhabdophis tigrinus. Deborah A. Hutchinson, Alan H. Savitzky, Akira Mori, Jerrold Meinwald, and Frank C. Schroeder, Chemoecology 2008, 18, 181-190.
59. Identification of indole glucosinolate breakdown products with antifeedant effects on Myzus persicae (green peach aphid). Kim, Jae Hak; Lee, Byong-Won; Schroeder, Frank; Jander, Georg, Plant J, 2008, 54. 1015-1026.
58. Identification of Xanthurenic Acid 8-O-β-D-Glucoside and Xanthurenic Acid 8-O-Sulfate as Human Natriuretic Hormones. Christopher D. Cain, Frank C. Schroeder, Stewart W. Shankel, Mark Mitchnick, Michael Schmertzler, and Neal S. Bricker, Proc. Natl. Acad. Sci. USA 2007, 104, 17873-17878.
57. Synthesis and Reactivity of [(silox)(2)Mo=NR](2)Hg (R = (t)Bu, (t)Amyl; silox = OSi(t)Bu(3)): Unusual Thermal Stability and Ready Nucleophilic Cleavage Rationalized by Electronic Factors. D. C. Rosenfeld, P. T. Wolczanski, K. A. Barakat, C. Buda, T. R. Cundari, F. C. Schroeder E. B. Lobkovsky, Inorg. Chem. 2007, 46, 9715-9735.
56. Grass roots chemistry: meta-Tyrosine, an herbicidal nonprotein amino acid. Cecile Bertin, Leslie A. Weston, Geeorg Jander, Tengfang Huang, Thomas Owens, Jerrold Meinwald, Frank C. Schroeder, Proc. Natl. Acad. Sci. USA 2007, 104, 16964-16969.
55. Small-molecule pheromones that control dauer development in Caenorhabditis elegans. Rebecca A. Butcher, Masaki Fujita, Frank C. Schroeder & Jon Clardy, Nat. Chem. Biol. 2007, 3, 420-422.
54. Biosynthesis of Thiamin Thiazole in Eukaryotes: Conversion of NAD to an Advanced Intermediate. Abhishek Chatterjee, Christopher T. Jurgenson, Frank C. Schroeder, Steven E. Ealick, and Tadhg P. Begley, J. Am. Chem. Soc. 2007, 129, 2914-2922.
53. Dietary Sequestration of Defensive Steroids in Nuchal Glands of the Asian Snake Rhabdophis tigrinus. Deborah Hutchinson, Akira Mori, Alan Savitzky, Gordon Burghardt, Xiaogang Wu, Jerrold Meinwald, Frank C. Schroeder, Proc. Natl. Acad. Sci. USA, 2007, 104, 2265-2270.
52. The identification of bacillaene, the product of the PksX megacomplex in Bacillus subtilis. Rebecca A. Butcher, Frank C. Schroeder, Michael A. Fischbach, Christopher T. Walsh, and Jon Clardy, Proc. Natl. Acad. Sci. USA, 2007, 104, 1506-1509.
51. Differential Analysis of 2D NMR Spectra: New Natural Products from a Pilot-Scale Fungal Extract Library. Frank C. Schroeder, Donna M. Gibson, Alice C. L. Churchill, Eric J. Wursthorn, Stuart B. Krasnoff, and Jon Clardy. Angew. Chem. Int. Ed. 2007, 46, 901 –904.
50. Enzymatic generation of the antimetabolite γ,γ-dichloroaminobutyrate by NRPS and mononuclear iron halogenase action in a streptomycete. Masashi Ueki, Danica P. Galonić, Frédéric H. Vaillancourt, Sylvie Garneau-Tsodikova, Ellen Yeh, David A. Vosburg, Frank C. Schroeder, Hiroyuki Osada, Christopher T. Walsh. Chem. Biol. 2006, 13, 1183-1191.
49. An Oligomerization Approach to Generating Skeletal Diversity. David A. Spiegel, Frank C. Schroeder, and Stuart L. Schreiber, J. Am. Chem. Soc. 2006, 128(46), 14766-14767.
48. Extending the scope of NMR spectroscopy with microcoil probes. Frank C. Schroeder, Matthew Gronquist, Angew. Chem. Int. Ed. 2006, 45, 7122-7131.
47. Phaeosphaeride A, an Inhibitor of STAT3-Dependent Signaling Isolated from an Endophytic Fungus. Katherine N. Maloney, Wenshan Hao, Jun Xu, Jay Gibbons, John Hucul, Deborah Roll, Sean F. Brady, Frank C. Schroeder, Jon Clardy, Org. Lett. 2006, 8, 4067-4070.
46. Small molecule signaling in Caenorhabditis elegans. Frank C. Schroeder, ACS Chem. Biol. 2006, 1, 198-200.
45. Thiamin Biosynthesis in Eukaryotes: Characterization of the Enzyme-Bound Product of Thiazole Synthase from Saccharomyces cerevisiae and Its Implications in Thiazole Biosynthesis. Abhishek Chatterjee, Christopher T. Jurgenson, Frank C. Schroeder, Steven E. Ealick, Tadhg P. Begley, J. Am. Chem. Soc. 2006, 128, 7158-7159.
44. Novel Isoquinoline Quinones from the Tunicate Ascidia virginea. Sven T. Possner, Frank C. Schroeder, Hans Tore Rapp, Volker Sinnwell, Stefan Franke, Wittko Francke,submitted.
43. Pinoresinol: a basic lignol of plant origin, appropriated for defensive purposes by a caterpillar. Frank C. Schroeder, Marta L. del Campo, Jacqualine B. Grant, Douglas B. Weibel, Scott R. Smedley, Kelly L. Bolton, Jerrold Meinwald, Thomas Eisner, Proc. Natl. Acad. Sci. USA 2006, 103(42), 15497-15501.
42. Shunning the night to elude the hunter: diurnal fireflies and the “femmes fatales”. Matthew Gronquist, Frank C. Schroeder, Helen Ghiradella, David Hill, Erin M. McCoy, Jerrold Meinwald and Thomas Eisner, Chemoecology 2006, 16, 1-5.
41. Exploring Uncharted Terrain in Nature's Structure Space Using Capillary NMR Spectroscopy: 13 Steroids from 50 Fireflies. Matthew Gronquist, Jerrold Meinwald, Thomas Eisner, Frank C. Schroeder, J. Am. Chem. Soc. 2005, 127(31), 10810-10811.
40. The Psammaplysenes, Specific Inhibitors of FOXO1a Nuclear Export. Frank C. Schroeder, Tweeny R. Kau, Pamela A. Silver, Jon Clardy, J. Nat. Prod. 2005, 68, 574.
39. Chiral Silylation Reagents: Determining Configuration via NMR-Spectroscopic Co-Analysis. Frank C. Schroeder, Douglas B. Weibel, and Jerrold Meinwald, Org. Lett. 2004, 6, 3019-3022.
38. A New Approach to Natural Products Discovery Exemplified by the Identification of Sulfated Nucleosides in Spider Venom. Andrew E. Taggi, Jerrold Meinwald, Frank C. Schroeder, J. Am. Chem. Soc. 2004, 126, 10364-10369.
37. Defensive ‘flocculent’ emissions in a Tiger moth, Homoeocera stictosoma (Arctiidae, Actiinae). Jayne E. Yack, William E. Conner, Tiffany A. Timbers, Annette Aiello, Frank C. Schroeder, J. Lep. Soc., 2003, 34-47.
36. A chemical genetic screen identifies inhibitors of regulated nuclear export of a Forkhead transcription factor in PTEN-deficient tumor cells. Tweeny R. Kau, Frank C. Schroeder, Cheryl L. Wojciechowski, Jean J. Zhou, Tom Roberts, Jon Clardy, William R. Sellers, Pamela A. Silver, Cancer Cell, 2003, 463-476.
35. New Non-Glycosidic Diterpenes from Leaves of Stevia rebaudiana. B.D. McGarvey, A.B. Attygalle, A.N. Starratt, J.E. Brandle, B. Xiang, F.C. Schroeder, and J. Meinwald, J. Nat. Prod. 66(10), 2003, 1395-1398.
34. Isobutylamides of Unsaturated Fatty Acids from Chrysanthemum morifolium Associated with Host-Plant Resistance against the Western Flower Thrips. Tsao, Rong; Attygalle, Athula B.; Schroeder, Frank C.; Marvin, Chris H.; McGarvey, Brian D. J. Natl. Prod. 66(9), 2003, 1229-1231.
33. New Silyl Ether Reagents for the Absolute Stereochemical Determination of Secondary Alcohols. R. Thomas Williamson, Ana C. Barrios Sosa, Abhijit Mitra, Pamela J. Seaton, Douglas B. Weibel, Frank C. Schroeder, Jerrold Meinwald, and Frank E. Koehn, Org. Lett. 5, 2003, 1745-1748.
32. Synthesis of Mayolene-16 and Mayolene-18: Larval Defensive Lipids from the European Cabbage Butterfly. Douglas B. Weibel, Laura E. Shevy, Frank C. Schroeder, Jerrold Meinwald, J. Org. Chem. 2002, 67(17), 5896-5900.
31. Chemical defense and aposematism: the case of Utetheisa galapagensis. Lázaro Roque-Albelo, Frank C. Schroeder, William E. Conner, Alexander Bezzerides, E. Richard Hoebeke, Jerrold Meinwald, Thomas Eisner, Chemoecology 2002, 12, 153-157.
30. Mayolenes: Labile defensive lipids from the glandular hairs of a caterpillar (Pieris rapae). Scott R. Smedley, Frank C. Schroeder, Douglas B. Weibel, Jerrold Meinwald, Katie A. Lafleur, J. Alan Renwick, Ronald Rutowski, and Thomas Eisner, Proc. Natl. Acad. Sci. USA 2002, 99, 6822-6827.
29. Hydroquinone: a general phagostimulating pheromone in termites. Judith Reinhard, Michael J. Lacey, Fernando Ibarra, Frank Schroeder, Manfred Kaib, Michael Lenz, J. Chem. Ecol., 2002, 28, 1-14.
28. Production of a cyanogenic secretion by a thyridid caterpillar. D. Christopher Darling, Frank C. Schroeder, Jerrold Meinwald, Maria Eisner, Thomas Eisner, Naturwissenschaften 2001, 88, 306-309.
27. Host recognition by the tobacco hornworm is mediated by a host plant compound. Marta L. del Campo, Carol I. Miles, Frank C. Schroeder, Caroline Mueller, Ronald Booker, J. Alan Renwick, Nature 2001, 411, 186-189.
26. Chemical defense: bestowal of a nuptial alkaloidal garment by a male moth upon its mate. William E. Conner, Ruth Boada, Frank C. Schroeder, Andres Gonzales, Jerrold Meinwald, Thomas Eisner, Proc. Natl. Acad. Sci. USA 2000, 97, 14406-14411.
25. Synthesis of Macrocyclic Insect-Derived Alkaloids. Jay J. Farmer, Frank C. Schroeder, Jerrold Meinwald, Helv. Chim. Acta 2000, 83, 2594-2606.
24. A Combinatorial Library of Macrocyclic Polyamines Produced by a Ladybird Beetle. Frank C. Schroeder, Jay J. Farmer, Athula B. Attygalle, Scott R. Smedley, Thomas Eisner, and Jerrold Meinwald, J. Am. Chem. Soc. 2000, 122, 3628-3634.
23. Chiral Silylation Reagents for the Determination of Absolute Configuration by NMR Spectroscopy. Douglas B. Weibel, Tameka R. Walker, Frank C. Schroeder, Jerrold Meinwald, Org. Lett. 2000, 2, 2381-2383.
22. Metabolic Transformations of Acquired Lucibufagins by Firefly "Femmes Fatales". Andres Gonzales, Frank C. Schroeder, Athula B. Attygalle, Ales Svatos, Jerrold Meinwald, Thomas Eisner, Chemoecology 1999, 9, 105-112.
21. Miriamin, a defensive diterpene from the eggs of a land slug (Arion sp.). Frank C. Schroeder, Andrés Gonzalez, Thomas Eisner, and Jerrold Meinwald, Proc. Natl. Acad. Sci. USA 1999, 96, 13620-13525.
20. N-Methylquinolinium 2-carboxylate, a Defensive Betaine from Photuris versicolor Fireflies. A. Gonzalez, F. C. Schroeder, T. Eisner, J. Meinwald, J. Nat. Prod. 1999, 62, 378-380.
19. Synthesis of Myrmicarin 217, a Pyrrolo[2,1,5-cd]indolizidine from Ants. Frank Schröder, Wittko Francke, Tetrahedron 1998, 54, 5259-5264.
18. Sex Pheromone of Female Vine Bud Moth, Theresimima ampellophaga, Comprises (2S)‑Butyl-(7Z)-tetradecenoate. M. Subchev, A. Harizanov, W. Francke, S. Franke, E. Plass, A. Reckziegel, F. Schröder, J.A. Pickett, L. J. Wadhams, C. M. Woodcock, J. Chem. Ecol. 1998, 24, 1141-1152.
17. Induced Chemical Defense in Plants. Frank Schröder, Angew. Chem. Int. Ed. 1998, 37, 1213-1216.
16. Polyazamacrolides from Ladybird Beetles: Ring-Size Selective Oligomerization. Frank C. Schröder, Scott R. Smedley, Leah K. Gibbons, Jay J. Farmer, Athula B. Attygalle, Thomas Eisner, Jerrold Meinwald, Proc. Natl. Acad. Sci. USA 1998, 95, 13387-13391.
15. Psylloborine A, a New Dimeric Alkaloid from Ladybird Beetles. Frank C. Schröder, Till Tolasch, Tetrahedron 1998, 54, 12243-12248.
14. Absolute Configuration of the Polyazamacrolides, Macrocyclic Polyamines Produced by a Ladybird Beetle. Frank C. Schröder, Jay J. Farmer, Scott R. Smedley, Thomas Eisner, Jerrold Meinwald, Tetrahedron Lett. 1998, 39, 6625-6628.
13. Combinatorial Chemistry in Insects: A Library of Defensive Macrocyclic Polyamines. Frank C. Schröder, Jay J. Farmer, Athula B. Attygalle, Scott R. Smedley, Thomas Eisner, Jerrold Meinwald, Science 1998, 281, 428-431.
12. Cysteine-glutathione disulfide, the sperm-release pheromone of the marine polychaete Nereis succinea (Annelida: Polychaeta). E. Zeeck, C. T. Müller, M. Beckmann, J. D. Hardege, U. Papke, V. Sinnwell, F. C. Schröder, W. Francke, Chemoecology 1998, 8, 33-38.
11. Mirasorvone: A Masked 20-Ketopregnane from the Defensive Secretion of a Diving Beetle (Thermonectus marmoratus). Jerrold Meinwald, Qing Huang, Jan Vrkoc, Kithsiri B. Herath, Zhi-Cai Yang, Frank Schröder, Athula B. Attygalle, Vikram K. Iyengar, R. C. Morgan, and Thomas Eisner, Proc. Natl. Acad. Sci. USA 1998, 95, 2733-2737.
10. Myrmicarin 663: A New Decacyclic Alkaloid from Ants. Frank Schröder, Volker Sinnwell, Horst Baumann, Manfred Kaib, Wittko Francke, Angew. Chem. Int. Ed. 1997, 36, 77-80.
9. Synthesis of (1S,2R,5R)-2-Ethyl-1,5-dimethyl-6,8-dioxabicyclo[3.2.1]octane, the Aggregation Pheromone of Male Beech Bark Beetles, Taphrorychus bicolor (Col., Scol.). Wittko Francke, Frank Schröder, Ulrich Kohnle, M. Simon, Liebigs Ann. 1996, 1523-1527.
8. A New Family of Tricyclic Alkaloids from Myrmicaria Ants. Frank Schröder, Stephan Franke, Wittko Francke, Horst Baumann, Manfred Kaib, Jacques M. Pasteels, Desire Daloze, Tetrahedron 1996, 52, 13539-13546.
7. 3,4-Epoxy-8-deoxycumambrin B, a Sesquiterpene Lactone from Tanacetum parthenium. Martina Milbrodt, Frank Schröder, Wilfried A. König, Phytochemistry 1996, 44, 471-474.
6. Myrmicarin 430A: a New Heptacyclic Alkaloid from Myrmicaria Ants. Frank Schröder, Horst Baumann, Manfred Kaib, Volker Sinnwell, Wiiko Francke, Chem. Commun. 1996, 2139-2140.
5. Identification and Synthesis of New Bicyclic Acetals from the Mountain Pine Beetle, Dendroctonus ponderosae Hopkins (Col.: Scol.). Wittko Francke, Frank Schröder, Peter Philipp, Holger Meyer, Volker Sinnwell, Gerhard Gries, Bioorg. Med. Chem. 1996, 4, 363-374.
4. Semiochemicals in Bark Beetles: New Results, Remarks and Reflections. W. Francke, J. Bartels, H. Meyer, F. Schröder, U. Kohnle, E. Baader, J. P. Vite, J. Chem. Ecol. 1995, 21, 1043-1063.
3. The Male Pheromone of the Old House Borer Hylotrupes bajulus (L.) (Coleoptera: Cerambycidae): Identification and Response. Regina Fettköther, Konrad Dettner, Frank Schröder, Holger Meyer, Wittko Francke, Uwe Noldt, Experientia 1995, 51, 270-277.
2. New Alkaloids from Ants: Identification and Synthesis of (3R,5S,9R)-3-Butyl-5-(1-oxopropyl)-indolizidine and (3R,5R,9R)-3-Butyl-5-(1-oxopropyl)indolizidine, Constituents of the Poison Gland Secretion in Myrmicaria eumenoides (Hymenoptera, Formicidae). Wittko Francke, Frank Schröder, Felix Walter, Volker Sinnwell, Horst Baumann, Manfred Kaib, Liebigs Ann. 1995, 965-977.
1. Synthesis of (3R)-3-Hydroxy-2-hexanone, (2R,3R)-2,3-Hexanediol and (2S,3R)-2,3-Hexanediol, the Male Sex Pheromone of Hylotrupes bajulus and Pyrrhidium sanguineum (Cerambycidae). Frank Schröder, Regina Fettköther, Uwe Noldt, Wilfried A. König, Wittko Francke, Liebigs Ann. Chem. 1994, 1211-1218.